biological processes – Communicable Diseases Research

Association of iron-related biomarkers with severity and mortality in COVID-19 patients

Article

Published on 2022-12-012022-11-15
Journal: Journal of trace elements in medicine and biology
[Category] COVID19(2023년), SARS, 바이오마커, 치료기술,

Correlates with Vaccine Protective Capacity and COVID-19 Disease Symptoms Identified by Serum Proteomics in Vaccinated Individuals

Article

Published on 2022-09-132022-11-15
Journal: Molecules
[Category] SARS, 변종, 유전자 메커니즘, 진단,

[키워드] acute respiratory syndrome Algorithm allergy Analysis Asymptomatic autoantibodies autoantibody biological processes Biomarker Capacity caused characterized circulating Cohort coronavirus coronavirus disease correlated COVID-19 disease disease severity disease-associated effective intervention Efficacy epitope Evidence Genetic HBV Identified Immunoglobulin immunology implementation individual individuals mechanism non-severe cases pandemic PCR-negative PCR-positive PCR-positive individual profile Protective Protein Proteins proteomic proteomics purpura Quantitative RBD reducing response to vaccination risk SARS-CoV-2 severe disease severe symptom spike receptor-binding domain Symptom thrombosis understanding uninfected vaccinated individual Vaccine Vaccine development vaccine. virus transmission virus variant viruses with COVID-19
[DOI] 10.3390/molecules27185933 PMC 바로가기

Presepsin Predicts Severity and Secondary Bacterial Infection in COVID-19 by Bioinformatics Analysis

Article

Published on 2022-09-062022-11-15
Journal: Computational and Mathematical Methods in Medicine
[Category] SARS, 바이오마커,

[키워드] acute respiratory disease Analysis AUC biological processes caused CD14 cellular components Coronavirus pneumonia COVID-19 COVID-19 patient Critical datasets deaths DEGs Diagnosis diagnostic value differentially expressed gene downregulated enrichment analysis expression function Gene ontology KEGG Kyoto limit majority moderate molecular function nonsurvivor novel novel coronavirus SARS-CoV-2 Pathway enrichment analysis PPI predict Prognosis protein-protein interaction screened secondary secondary bacterial infection selected severe COVID-19 severe COVID-19 patient severity significantly significantly higher significantly increased survivor Treatment upregulated utility was performed
[DOI] 10.1155/2022/9914927 PMC 바로가기

Antiviral drugs against influenza: Treatment methods, environmental risk assessment and analytical determination

Review article

Published on 2022-09-012022-10-05
Journal: Journal of environmental management
[Category] 치료제,

Gene Network Analysis of the Transcriptome Impact of SARS-CoV-2 Interacting MicroRNAs in COVID-19 Disease

COVID-19 질병에서 SARS-CoV-2 상호작용 MicroRNA의 전사체 영향에 대한 유전자 네트워크 분석

Review

Published on 2022-08-172022-09-11
Journal: International Journal of Molecular Sciences
[Category] SARS, 유전자 메커니즘,

[키워드] affected Analysis biochemical biological processes Cell cell cycle cell surface receptor changes characterized COVID-19 COVID-19 disease cytokine death DEGs differentially expressed differentially expressed gene Differentially expressed genes downregulated exploratory FIVE functional enrichment Functional enrichment analysis Gene Expression gene network Health Organization heart Impact involved kidneys list lung Lymph node microRNA MicroRNAs mitochondrial mitotic mitotic cell modulation molecular Multiorgan multiorgan disease network network analysis network analysis. pathological mechanism Pathways Perspective predicted provide reported SARS-CoV-2 SARS-CoV-2 virus signaling pathway submitted surface receptor target tissue tissues transcriptomes translated upregulated WHO with COVID-19 World Health Organization
[DOI] 10.3390/ijms23169239 PMC 바로가기 [Article Type] Review

Proteomic Profile of Procoagulant Extracellular Vesicles Reflects Complement System Activation and Platelet Hyperreactivity of Patients with Severe COVID-19

응고촉진 세포외 소포의 단백질 프로파일은 중증 COVID-19 환자의 보체 시스템 활성화 및 혈소판 과민반응을 반영합니다

Article

Published on 2022-07-222022-09-11
Journal: Frontiers in Cellular and Infection Microbiology
[Category] COVID19(2023년), SARS, 유전자 메커니즘,

[키워드] acute inflammatory response alteration analyzed applied approach biological processe biological processes Biomarker Biomarkers cascades caused change changes in circulating Coagulation complement complement factors computational analysis COVID-19 COVID-19 patients Cytometry degranulation disease pathogenesis Diseases EVs experiment expressed extracellular vesicle Extracellular vesicles Flow flow cytometry group healthy donor healthy donors identify increase in indicated infected with SARS-CoV-2 LC-MS LC-MS/MS molecular pathophysiological Patient plasma Platelet Platelets procoagulant procoagulant activity profile progression Protein proteome proteomic SARS-CoV-2 SEC severe COVID-19 severe COVID-19 patients severity of COVID-19 significant changes in size exclusion chromatography System the disease tissue Tissue Factor Tissue factor. total protein Vesicle was performed
[DOI] 10.3389/fcimb.2022.926352 PMC 바로가기 [Article Type] Article

Characterisation of the blood RNA host response underpinning severity in COVID-19 patients

COVID-19 환자의 중증도를 뒷받침하는 혈액 RNA 숙주 반응의 특성화

Article

Published on 2022-07-172022-09-11
Journal: Scientific Reports
[Category] COVID19(2023년), SARS, 바이오마커, 유전자 메커니즘, 치료법,

[키워드] abundance addition Administered Alter Analysis asymptomatic infection biological processe biological processes Blood blood transcriptome clinical manifestations COVID-19 patient COVID-19 severity differential expression Differential expression analysis disease dysregulation Genes groups highlight host response immune dysregulation Immunoglobulin immunomodulatory Increasing individual Infection inflammatory immune response life-threatening macrophages Mild moderate neutrophil Neutrophils offer Pairwise comparison pairwise comparisons Pathway enrichment analysis Pathways performed progression Research RNA SARS-CoV-2 severe COVID-19 severe disease severity Transcriptome Treatment unique upregulation Whole blood Whole blood transcriptomics
[DOI] 10.1038/s41598-022-15547-2 PMC 바로가기 [Article Type] Article

Metabolite, protein, and tissue dysfunction associated with COVID-19 disease severity

COVID-19 질병 중증도와 관련된 대사 산물, 단백질 및 조직 기능 장애

Article

Published on 2022-07-162022-09-11
Journal: Scientific Reports
[Category] 바이오마커, 유전자 메커니즘, 진단, 치료기술, 치료법,

[키워드] age analysis anatomical approach biochemical pathway Biochemical pathways biological processe biological processes blood count blood count test changes in Characteristics clinical information complete blood count conjunction contribute COVID-19 Critical disease disease severity dysfunction Factor functional Gender Genome Health Health status Host Infection information Injury Interaction investigated liver lung machine learning algorithm Machine learning algorithms metabolite metabolites metabolomics molecular mechanism molecular mechanisms outcome Patient patient data predict presenting symptom profiles progression Protein proteomics provide response significant enrichment systemic inflammation tissue Treatment treatment of COVID-19 unstructured data with COVID-19
[DOI] 10.1038/s41598-022-16396-9 PMC 바로가기 [Article Type] Article

Hypoxia signaling in human health and diseases: implications and prospects for therapeutics

Reviews

Published on 2022-07-072022-10-05
Journal: Signal Transduction and Targeted Therapy
[Category] 신약개발,

Joint impact of key air pollutants on COVID-19 severity: prediction based on toxicogenomic data analysis

주요 대기 오염 물질이 COVID-19 심각도에 미치는 공동 영향: 독성 유전체 데이터 분석을 기반으로 한 예측

Article

Published on 2022-07-072022-09-11
Journal: Arhiv za higijenu rada i toksikologiju
[Category] 유전자 메커니즘,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Air pollution AML Analysis binding biological process biological processe biological processes carbon monoxide CEBPA citokini Comparative Complication coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 complication COVID-19 complications COVID-19 patient COVID-19 transmission CTD cytokine Cytokine storm Cytokines Data analysis death rate determine disease disease complications Diseases DisGeNET dušikov dioksid English Fever Final GeneMANIA Genes identify IL10 IL1B IL6 in silico indicate Inflammation interactions komplikacije bolesti lebdeće čestice molecular molecular function network nitrogen nitrogen dioxide onečišćivači zraka Other ozon Ozone Particulate Particulate matter pathway Periodic fever physical poremećaj funkcije gena researcher resulting SARS-CoV-2 severe acute respiratory syndrome Coronavirus severity sulphur dioxide sumporov dioksid syndrome the cytokine storm TNF TNFRSF1A ugljikov monoksid.
[DOI] 10.2478/aiht-2022-73-3631 PMC 바로가기 [Article Type] Article